Ontology highlight
ABSTRACT:
SUBMITTER: Abidi O
PROVIDER: S-EPMC3250372 | biostudies-literature | 2011
REPOSITORIES: biostudies-literature
Abidi Omar O Knari Sara S Sefri Hajar H Charif Majida M Senechal Audrey A Hamel Christian C Rouba Hassan H Zaghloul Khalid K El Kettani Asmaa A Lenaers Guy G Barakat Abdelhamid A
Molecular vision 20111230
<h4>Purpose</h4>Retinoblastoma (RB), the most common intraocular tumor occurring in infancy and early childhood, is most often related to mutations in the RB1 gene. In this study, we screened the RB1 germline mutations in 41 unrelated Moroccan patients with retinoblastoma, 25 heritable cases, and 16 sporadic unilateral cases.<h4>Methods</h4>After complete ophthalmic examinations were performed and consent obtained, DNA was extracted from peripheral blood, and screening of RB1 mutations was perfo ...[more]