Ontology highlight
ABSTRACT:
SUBMITTER: Giaccone L
PROVIDER: S-EPMC3251223 | biostudies-literature | 2011 Jun
REPOSITORIES: biostudies-literature
Giaccone Luisa L Storer Barry B Patriarca Francesca F Rotta Marcello M Sorasio Roberto R Allione Bernardino B Carnevale-Schianca Fabrizio F Festuccia Moreno M Brunello Lucia L Omedè Paola P Bringhen Sara S Aglietta Massimo M Levis Alessandro A Mordini Nicola N Gallamini Andrea A Fanin Renato R Massaia Massimo M Palumbo Antonio A Ciccone Giovannino G Storb Rainer R Gooley Ted A TA Boccadoro Mario M Bruno Benedetto B
Blood 20110413 24
Before the introduction of new drugs, we designed a trial where treatment of newly diagnosed myeloma patients was based on the presence or absence of HLA-identical siblings. First-line treatments included a cytoreductive autograft followed by a nonmyeloablative allograft or a second melphalan-based autograft. Here, we report long-term clinical outcomes and discuss them in the light of the recent remarkable advancements in the treatment of myeloma. After a median follow-up of 7 years, median over ...[more]