Ontology highlight
ABSTRACT:
SUBMITTER: Barrett JH
PROVIDER: S-EPMC3251256 | biostudies-literature | 2011 Oct
REPOSITORIES: biostudies-literature
Barrett Jennifer H JH Iles Mark M MM Harland Mark M Taylor John C JC Aitken Joanne F JF Andresen Per Arne PA Akslen Lars A LA Armstrong Bruce K BK Avril Marie-Francoise MF Azizi Esther E Bakker Bert B Bergman Wilma W Bianchi-Scarrà Giovanna G Bressac-de Paillerets Brigitte B Calista Donato D Cannon-Albright Lisa A LA Corda Eve E Cust Anne E AE Dębniak Tadeusz T Duffy David D Dunning Alison M AM Easton Douglas F DF Friedman Eitan E Galan Pilar P Ghiorzo Paola P Giles Graham G GG Hansson Johan J Hocevar Marko M Höiom Veronica V Hopper John L JL Ingvar Christian C Janssen Bart B Jenkins Mark A MA Jönsson Göran G Kefford Richard F RF Landi Giorgio G Landi Maria Teresa MT Lang Julie J Lubiński Jan J Mackie Rona R Malvehy Josep J Martin Nicholas G NG Molven Anders A Montgomery Grant W GW van Nieuwpoort Frans A FA Novakovic Srdjan S Olsson Håkan H Pastorino Lorenza L Puig Susana S Puig-Butille Joan Anton JA Randerson-Moor Juliette J Snowden Helen H Tuominen Rainer R Van Belle Patricia P van der Stoep Nienke N Whiteman David C DC Zelenika Diana D Han Jiali J Fang Shenying S Lee Jeffrey E JE Wei Qingyi Q Lathrop G Mark GM Gillanders Elizabeth M EM Brown Kevin M KM Goldstein Alisa M AM Kanetsky Peter A PA Mann Graham J GJ Macgregor Stuart S Elder David E DE Amos Christopher I CI Hayward Nicholas K NK Gruis Nelleke A NA Demenais Florence F Bishop Julia A Newton JA Bishop D Timothy DT
Nature genetics 20111009 11
We report a genome-wide association study for melanoma that was conducted by the GenoMEL Consortium. Our discovery phase included 2,981 individuals with melanoma and 1,982 study-specific control individuals of European ancestry, as well as an additional 6,426 control subjects from French or British populations, all of whom were genotyped for 317,000 or 610,000 single-nucleotide polymorphisms (SNPs). Our analysis replicated previously known melanoma susceptibility loci. Seven new regions with at ...[more]