Predictive role of XRCC5/XRCC6 genotypes in digestive system cancers.
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ABSTRACT:
SUBMITTER: Yang MD
PROVIDER: S-EPMC3251741 | biostudies-literature | 2011 Dec
REPOSITORIES: biostudies-literature
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Predictive role of XRCC5/XRCC6 genotypes in digestive system cancers.
Yang Mei-Due MD Tsai Chia-Wen CW Chang Wen-Shin WS Tsou Yung-An YA Wu Cheng-Nan CN Bau Da-Tian DT
World journal of gastrointestinal oncology 20111201 12
Cancers are a worldwide concern; oral, esophageal and gastrointestinal cancers represent important causes of cancer-related mortality and contribute to a significant burden of human health. The DNA repair systems are the genome caretakers, playing a critical role in the initiation and progression of cancers. However, the association between the genomic variations of DNA repair genes and cancer susceptibility is not well understood. This review focuses on the polymorphic genotypes of the non-homo ...[more]
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