Ontology highlight
ABSTRACT:
SUBMITTER: Montjean D
PROVIDER: S-EPMC3252406 | biostudies-literature | 2012 Jan
REPOSITORIES: biostudies-literature
Montjean Debbie D De La Grange Pierre P Gentien David D Rapinat Audrey A Belloc Stéphanie S Cohen-Bacrie Paul P Menezo Yves Y Benkhalifa Moncef M
Journal of assisted reproduction and genetics 20111012 1
<h4>Purpose</h4>Investigate in what extent sperm transcriptome of infertile men is different from that of fertile individuals.<h4>Methods</h4>Semen samples were collected for determination of sperm parameters as well as for RNA isolation. Gene expression profile was investigated in spermatozoa of 8 infertile and 3 fertile men by microarray analysis using the Affymetrix Chip HG-U133 Plus 2.0.<h4>Result(s)</h4>We observed up to 33-fold reduction expression of genes involved in spermatogenesis and ...[more]