Dataset Information

The impact of menopause on health-related quality of life: results from the STRIDE longitudinal study.

ABSTRACT:

Purpose

We examine the impact of menopausal status, beyond menopausal symptoms, on health-related quality of life (HRQoL).

Methods

Seven hundred thirty-two women aged 40-65, regardless of health condition or menopausal status, were enrolled from single general internal medicine practice. Women completed annual questionnaires including HRQoL, and menopausal status and symptoms.

Results

The physical health composite of the RAND-36 is lower in late peri (45.6, P < .05), early post (45.4, P < .05), and late postmenopausal women (44.6, P < .01), and those who report a hysterectomy (44.2, P < .01) compared to premenopausal women (47.1), with effect sizes of Cohen's d = .12-.23. The mental health composite of the RAND-36 is lower in late peri (44.7, P < .01), early post (44.9, P < .01), and late postmenopausal women (45.0, P < .05) and those who report a hysterectomy (44.2, P < .01) compared to premenopausal women (46.8), with effect sizes of Cohen's d = .15-.20. Findings are comparable adjusted for menopausal symptom frequency and bother.

Conclusions

Over a 5-year follow-up period, we found a negative impact of menopause on some domains of HRQoL, regardless of menopausal symptoms. Clinicians should be aware of this relationship and work to improve HRQoL, rather than expect it to improve spontaneously when menopausal symptoms resolve.

SUBMITTER: Hess R

PROVIDER: S-EPMC3252474 | biostudies-literature | 2012 Apr

REPOSITORIES: biostudies-literature

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Publications

The impact of menopause on health-related quality of life: results from the STRIDE longitudinal study.

Hess Rachel R Thurston Rebecca C RC Hays Ron D RD Chang Chung-Chou H CC Dillon Stacey N SN Ness Roberta B RB Bryce Cindy L CL Kapoor Wishwa N WN Matthews Karen A KA

Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation 20110714 3

<h4>Purpose</h4>We examine the impact of menopausal status, beyond menopausal symptoms, on health-related quality of life (HRQoL).<h4>Methods</h4>Seven hundred thirty-two women aged 40-65, regardless of health condition or menopausal status, were enrolled from single general internal medicine practice. Women completed annual questionnaires including HRQoL, and menopausal status and symptoms.<h4>Results</h4>The physical health composite of the RAND-36 is lower in late peri (45.6, P < .05), early ...[more]

PMID: 21755412

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Dataset Information

The impact of menopause on health-related quality of life: results from the STRIDE longitudinal study.

Purpose

Methods

Results

Conclusions

Publications

The impact of menopause on health-related quality of life: results from the STRIDE longitudinal study.

Similar Datasets

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