Planar-bilayer activities of linear oligoester bolaamphiphiles.
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ABSTRACT:
SUBMITTER: Chui JK
PROVIDER: S-EPMC3252859 | biostudies-literature | 2011
REPOSITORIES: biostudies-literature
Publications
Planar-bilayer activities of linear oligoester bolaamphiphiles.
Chui Jonathan K W JK Fyles Thomas M TM Luong Horace H
Beilstein journal of organic chemistry 20111122
Voltage-clamp experiments of eight oligoester bolaamphiphiles in two subclasses are described. Syntheses of three new terephthalate-based compounds were achieved in three linear steps. Together with five previously described, related compounds, the ion transport activity was assessed by means of the voltage-clamp technique. All of the compounds show multiple types of conductance behavior in planar bilayers, a subset of which was exponentially voltage-dependent. The varied and irregular activitie ...[more]
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