Midkine in inflammation.
Ontology highlight
ABSTRACT:
SUBMITTER: Weckbach LT
PROVIDER: S-EPMC3253530 | biostudies-literature | 2011
REPOSITORIES: biostudies-literature
Publications
Midkine in inflammation.
Weckbach Ludwig T LT Muramatsu Takashi T Walzog Barbara B
TheScientificWorldJournal 20111227
The 13 kDa heparin-binding growth factor midkine (MK) was originally identified as a molecule involved in the orchestration of embryonic development. Recent studies provided evidence for a new role of MK in acute and chronic inflammatory processes. Accordingly, several inflammatory diseases including nephritis, arthritis, atherosclerosis, colitis, and autoimmune encephalitis have been shown to be alleviated in the absence of MK in animal models. Reduced leukocyte recruitment to the sites of infl ...[more]
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