Ontology highlight
ABSTRACT:
SUBMITTER: Watts RE
PROVIDER: S-EPMC3255690 | biostudies-literature | 2012 Jan
REPOSITORIES: biostudies-literature
Watts Rebecca E RE Totsika Makrina M Challinor Victoria L VL Mabbett Amanda N AN Ulett Glen C GC De Voss James J JJ Schembri Mark A MA
Infection and immunity 20110919 1
The molecular mechanisms that define asymptomatic bacteriuria (ABU) Escherichia coli colonization of the human urinary tract remain to be properly elucidated. Here, we utilize ABU E. coli strain 83972 as a model to dissect the contribution of siderophores to iron acquisition, growth, fitness, and colonization of the urinary tract. We show that E. coli 83972 produces enterobactin, salmochelin, aerobactin, and yersiniabactin and examine the role of these systems using mutants defective in sideroph ...[more]