Ontology highlight
ABSTRACT:
SUBMITTER: Assfalg R
PROVIDER: S-EPMC3258137 | biostudies-literature | 2012 Jan
REPOSITORIES: biostudies-literature
Assfalg Robin R Lebedev Anton A Gonzalez Omar Garcia OG Schelling Adrian A Koch Sylvia S Iben Sebastian S
Nucleic acids research 20110928 2
TFIIH is a multisubunit factor essential for transcription initiation and promoter escape of RNA polymerase II and for the opening of damaged DNA double strands in nucleotide excision repair (NER). In this study, we have analyzed at which step of the transcription cycle TFIIH is essential for transcription by RNA polymerase I. We demonstrate that TFIIH associates with the rDNA promoter and gene-internal sequences and leaves the rDNA promoter in a complex with RNA polymerase I after start of tran ...[more]