Ontology highlight
ABSTRACT:
SUBMITTER: Tomlinson GS
PROVIDER: S-EPMC3258543 | biostudies-literature | 2011 Nov
REPOSITORIES: biostudies-literature
Tomlinson Gillian S GS Cashmore Tamaryn J TJ Elkington Paul T G PT Yates John J Lehloenya Rannakoe J RJ Tsang Jhen J Brown Michael M Miller Robert F RF Dheda Keertan K Katz David R DR Chain Benjamin M BM Noursadeghi Mahdad M
European journal of immunology 20110830 11
The tuberculin skin test (TST) is a model of integrated innate and adaptive human immune responses to Mycobacterium tuberculosis, but the component processes that are involved in this model have not previously been defined in vivo. We used transcriptional profiling to study these responses within the TST at molecular and system levels. Skin biopsies from TST injection sites were examined in subjects classified as TST(+) or TST(-) by clinical and histological criteria. Genome-wide expression ar ...[more]