Ontology highlight
ABSTRACT:
SUBMITTER: Czepielewski RS
PROVIDER: S-EPMC3258617 | biostudies-literature | 2012 Jan
REPOSITORIES: biostudies-literature
Czepielewski Rafael Sanguinetti RS Porto Bárbara Nery BN Rizzo Lucas Bortolotto LB Roesler Rafael R Abujamra Ana Lúcia AL Pinto Larissa Garcia LG Schwartsmann Gilberto G Cunha Fernando de Queiroz Fde Q Bonorino Cristina C
Proceedings of the National Academy of Sciences of the United States of America 20111227 2
Neutrophil migration to inflamed sites is crucial for both the initiation of inflammation and resolution of infection, yet these cells are involved in perpetuation of different chronic inflammatory diseases. Gastrin-releasing peptide (GRP) is a neuropeptide that acts through G protein coupled receptors (GPCRs) involved in signal transmission in both central and peripheral nervous systems. Its receptor, gastrin-releasing peptide receptor (GRPR), is expressed by various cell types, and it is overe ...[more]