Ontology highlight
ABSTRACT:
SUBMITTER: Haniu H
PROVIDER: S-EPMC3260041 | biostudies-literature | 2011
REPOSITORIES: biostudies-literature
International journal of nanomedicine 20111221
We examined differences in cellular responses to multi-walled carbon nanotubes (MWCNTs) using malignant pleural mesothelioma cells (MESO-1), bronchial epithelial cells (BEAS-2B), neuroblastoma cells (IMR-32), and monoblastic cells (THP-1), before and after differentiation. MESO-1, BEAS-2B and differentiated THP-1 cells actively endocytosed MWCNTs, resulting in cytotoxicity with lysosomal injury. However, cytotoxicity did not occur in IMR-32 or undifferentiated THP-1 cells. Both differentiated an ...[more]