Ontology highlight
ABSTRACT:
SUBMITTER: Stone CB
PROVIDER: S-EPMC3260263 | biostudies-literature | 2012
REPOSITORIES: biostudies-literature
Stone Chris B CB Sugiman-Marangos Seiji S Bulir David C DC Clayden Rob C RC Leighton Tiffany L TL Slootstra Jerry W JW Junop Murray S MS Mahony James B JB
PloS one 20120117 1
Type III secretion (T3S) is an essential virulence factor used by gram-negative pathogenic bacteria to deliver effector proteins into the host cell to establish and maintain an intracellular infection. Chlamydia is known to use T3S to facilitate invasion of host cells but many proteins in the system remain uncharacterized. The C. trachomatis protein CT584 has previously been implicated in T3S. Thus, we analyzed the CT584 ortholog in C. pneumoniae (Cpn0803) and found that it associates with known ...[more]