Ontology highlight
ABSTRACT:
SUBMITTER: Yan F
PROVIDER: S-EPMC3261535 | biostudies-literature | 2012 Jan
REPOSITORIES: biostudies-literature
Yan Fang F Gao Yu-Feng YF Lv Feng F Zhang Tian-Chen TC Li Xu X Yin Hua-Fa HF
World journal of gastroenterology 20120101 4
<h4>Aim</h4>To investigate the association between three tag single nucleotide polymorphisms (tagSNPs) in interferon regulatory factors (IRF3) and the genetic susceptibility to chronic hepatitis B virus (HBV) infection.<h4>Methods</h4>We performed a case-control study of 985 Chinese cases of chronic HBV infection and 294 self-limiting HBV-infected individuals as controls. Three tagSNPs in IRF3 (rs10415576, rs2304204, rs2304206) were genotyped with the Multiplex SNaPshot technique. The genotype a ...[more]