The quantitative proteome of a human cell line.
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ABSTRACT:
SUBMITTER: Beck M
PROVIDER: S-EPMC3261713 | biostudies-literature | 2011 Nov
REPOSITORIES: biostudies-literature
Publications
The quantitative proteome of a human cell line.
Beck Martin M Schmidt Alexander A Malmstroem Johan J Claassen Manfred M Ori Alessandro A Szymborska Anna A Herzog Franz F Rinner Oliver O Ellenberg Jan J Aebersold Ruedi R
Molecular systems biology 20111108
The generation of mathematical models of biological processes, the simulation of these processes under different conditions, and the comparison and integration of multiple data sets are explicit goals of systems biology that require the knowledge of the absolute quantity of the system's components. To date, systematic estimates of cellular protein concentrations have been exceptionally scarce. Here, we provide a quantitative description of the proteome of a commonly used human cell line in two f ...[more]
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