Body fat distribution in women with familial partial lipodystrophy caused by mutation in the lamin A/C gene.
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ABSTRACT:
SUBMITTER: Monteiro LZ
PROVIDER: S-EPMC3263183 | biostudies-literature | 2012 Jan
REPOSITORIES: biostudies-literature
Publications
Body fat distribution in women with familial partial lipodystrophy caused by mutation in the lamin A/C gene.
Monteiro Luciana Z LZ Foss-Freitas Maria C MC Júnior Montenegro Renan M RM Foss Milton C MC
Indian journal of endocrinology and metabolism 20120101 1
Familial partial lipodystrophy (FPLD), Dunnigan variety, is an autosomal dominant disorder caused due to missense mutations in the lamin A/C (LMNA) gene encoding nuclear lamina proteins. Patients with FPLD are predisposed to metabolic complications of insulin resistance such as diabetes. We sought to evaluate and compare body fat distribution with dual-emission X-ray absorptiometry in women with and without FPLD and identify densitometric, clinical and metabolic features. ...[more]
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