Unknown

Dataset Information

0

Yeast one-hybrid assays for gene-centered human gene regulatory network mapping.

ABSTRACT: Gateway-compatible yeast one-hybrid (Y1H) assays provide a convenient gene-centered (DNA to protein) approach to identify transcription factors that can bind a DNA sequence of interest. We present Y1H resources, including clones for 988 of 1,434 (69%) predicted human transcription factors, that can be used to detect both known and new interactions between human DNA regions and transcription factors.

SUBMITTER: Reece-Hoyes JS 

PROVIDER: S-EPMC3263363 | biostudies-literature | 2011 Oct

REPOSITORIES: biostudies-literature

Json Xml
altmetric image

Publications

Gateway-compatible yeast one-hybrid (Y1H) assays provide a convenient gene-centered (DNA to protein) approach to identify transcription factors that can bind a DNA sequence of interest. We present Y1H resources, including clones for 988 of 1,434 (69%) predicted human transcription factors, that can be used to detect both known and new interactions between human DNA regions and transcription factors. ...[more]

Similar Datasets

Unknown Enhanced yeast one-hybrid assays for high-throughput gene-centered regulatory network mapping.
| S-EPMC3235803 | biostudies-literature
Unknown A yeast one-hybrid and microfluidics-based pipeline to map mammalian gene regulatory networks.
| S-EPMC3779800 | biostudies-literature
Unknown Comprehensive mapping of the human cytokine gene regulatory network.
| S-EPMC7708076 | biostudies-literature
Unknown Quantitative analysis of the ThrbCRM1-centered gene regulatory network.
| S-EPMC6504004 | biostudies-literature
Unknown Discovering human transcription factor physical interactions with genetic variants, novel DNA motifs, and repetitive elements using enhanced yeast one-hybrid assays.
| S-EPMC6724672 | biostudies-literature
Unknown Construction and characterization of a high-quality cDNA library of Cymbidium faberi suitable for yeast one- and two-hybrid assays.
| S-EPMC6966867 | biostudies-literature
Unknown A network of multiple regulatory layers shapes gene expression in fission yeast.
| S-EPMC1885965 | biostudies-literature
Unknown Removing auto-activators from yeast-two-hybrid assays by conditional negative selection.
| S-EPMC7943551 | biostudies-literature
Unknown Potential Direct Regulators of the Drosophila yellow Gene Identified by Yeast One-Hybrid and RNAi Screens.
| S-EPMC5068961 | biostudies-literature
Unknown Transcription Factor Activity Mapping of a Tissue-Specific in vivo Gene Regulatory Network.
| S-EPMC4584425 | biostudies-literature