Ontology highlight
ABSTRACT:
SUBMITTER: Barrisford GW
PROVIDER: S-EPMC3263689 | biostudies-literature | 2011
REPOSITORIES: biostudies-literature
International journal of surgical oncology 20110822
Familial renal cancer (FRC) is a heterogeneous disorder comprised of a variety of subtypes. Each subtype is known to have unique histologic features, genetic alterations, and response to therapy. Through the study of families affected by hereditary forms of kidney cancer, insights into the genetic basis of this disease have been identified. This has resulted in the elucidation of a number of kidney cancer gene pathways. Study of these pathways has led to the development of novel targeted molecul ...[more]