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Microsporidial keratitis in patients with hot springs exposure.


ABSTRACT: This retrospective study included 10 eyes of 9 patients diagnosed with microsporidial keratitis. All of them were known to contract this disease after taking baths in hot springs. The disease was diagnosed based on detecting microsporidia in corneal scrapings using Gram stain and the modified Kinyoun's acid-fast stain. The specimens from the last six patients were subjected to PCR and then sequencing. All of them revealed that the microorganism identified has a high similarity to Vittaforma corneae. Repeated debridement of the epithelial lesions successfully eradicated the microsporidial infection in all nine patients.

SUBMITTER: Fan NW 

PROVIDER: S-EPMC3264156 | biostudies-literature | 2012 Feb

REPOSITORIES: biostudies-literature

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Microsporidial keratitis in patients with hot springs exposure.

Fan Nai-Wen NW   Wu Chih-Chiau CC   Chen Te-Li TL   Yu Wei-Kuang WK   Chen Chien-Pei CP   Lee Shui-Mei SM   Lin Pei-Yu PY  

Journal of clinical microbiology 20111123 2


This retrospective study included 10 eyes of 9 patients diagnosed with microsporidial keratitis. All of them were known to contract this disease after taking baths in hot springs. The disease was diagnosed based on detecting microsporidia in corneal scrapings using Gram stain and the modified Kinyoun's acid-fast stain. The specimens from the last six patients were subjected to PCR and then sequencing. All of them revealed that the microorganism identified has a high similarity to Vittaforma corn  ...[more]

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