Emergence of carbapenem-resistant non-baumannii species of Acinetobacter harboring a blaOXA-51-like gene that is intrinsic to A. baumannii.
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ABSTRACT:
SUBMITTER: Lee YT
PROVIDER: S-EPMC3264228 | biostudies-literature | 2012 Feb
REPOSITORIES: biostudies-literature
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Emergence of carbapenem-resistant non-baumannii species of Acinetobacter harboring a blaOXA-51-like gene that is intrinsic to A. baumannii.
Lee Yi-Tzu YT Kuo Shu-Chen SC Chiang Mei-Chun MC Yang Su-Pen SP Chen Chien-Pei CP Chen Te-Li TL Fung Chang-Phone CP
Antimicrobial agents and chemotherapy 20111114 2
The bla(OXA-51)-like gene, originally intrinsic to Acinetobacter baumannii, had been detected in two clones of Acinetobacter nosocomialis and one clone of Acinetobacter genomic species "Close to 13TU." These bla(OXA-51)-like genes, all preceded by ISAba1, were located on plasmids that might have originated with A. baumannii. The plasmid-borne ISAba1--bla(OXA-51)-like confers a high level of carbapenem resistance and affects the accuracy of using bla(OXA-51)-like detection as a tool for different ...[more]
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