Ontology highlight
ABSTRACT:
SUBMITTER: Bessho H
PROVIDER: S-EPMC3265175 | biostudies-literature | 2012
REPOSITORIES: biostudies-literature
Bessho Hiroaki H Honda Shigeru S Kondo Naoshi N Kusuhara Sentaro S Tsukahara Yasutomo Y Negi Akira A
Molecular vision 20120118
<h4>Purpose</h4>To clarify the association of cluster of differentiation 36 (CD36) variants with polypoidal choroidal vasculopathy (PCV) and compare them with those in typical neovascular age-related macular degeneration (tAMD).<h4>Methods</h4>We included 349 Japanese AMD patients (210 PCV, 139 tAMD) and 198 age-matched controls. Four tag single-nucleotide polymorphisms (SNPs)-rs10499862, rs3173798, rs3211883, and rs3173800-in the CD36 region were genotyped using the TaqMan assay. Allelic and ge ...[more]