Ontology highlight
ABSTRACT:
SUBMITTER: Zeeberg BR
PROVIDER: S-EPMC3265467 | biostudies-literature | 2012
REPOSITORIES: biostudies-literature
Zeeberg Barry R BR Reinhold William W Snajder René R Thallinger Gerhard G GG Weinstein John N JN Kohn Kurt W KW Pommier Yves Y
PloS one 20120124 1
<h4>Background</h4>The NCI-60 is a panel of 60 diverse human cancer cell lines used by the U.S. National Cancer Institute to screen compounds for anticancer activity. In the current study, gene expression levels from five platforms were integrated to yield a single composite transcriptome profile. The comprehensive and reliable nature of that dataset allows us to study gene co-expression across cancer cell lines.<h4>Methodology/principal findings</h4>Hierarchical clustering revealed numerous clu ...[more]