Atrophy of spared gray matter tissue predicts poorer motor recovery and rehabilitation response in chronic stroke.
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ABSTRACT:
SUBMITTER: Gauthier LV
PROVIDER: S-EPMC3265680 | biostudies-literature | 2012 Feb
REPOSITORIES: biostudies-literature
Publications
Atrophy of spared gray matter tissue predicts poorer motor recovery and rehabilitation response in chronic stroke.
Gauthier Lynne V LV Taub Edward E Mark Victor W VW Barghi Ameen A Uswatte Gitendra G
Stroke 20111117 2
<h4>Background and purpose</h4>Although the motor deficit after stroke is clearly due to the structural brain damage that has been sustained, this relationship is attenuated from the acute to chronic phases. We investigated the possibility that motor impairment and response to constraint-induced movement therapy in patients with chronic stroke may relate more strongly to the structural integrity of brain structures remote from the lesion than to measures of overt tissue damage.<h4>Methods</h4>Vo ...[more]
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