Ontology highlight
ABSTRACT:
SUBMITTER: Langfelder P
PROVIDER: S-EPMC3265689 | biostudies-literature | 2012 Mar
REPOSITORIES: biostudies-literature
Langfelder Peter P Castellani Lawrence W LW Zhou Zhiqiang Z Paul Eric E Davis Richard R Schadt Eric E EE Lusis Aldons J AJ Horvath Steve S Mehrabian Margarete M
Biochimica et biophysica acta 20110723 3
We report a systems genetic analysis of high density lipoprotein (HDL) levels in an F2 intercross between inbred strains CAST/EiJ and C57BL/6J. We previously showed that there are dramatic differences in HDL metabolism in a cross between these strains, and we now report co-expression network analysis of HDL that integrates global expression data from liver and adipose with relevant metabolic traits. Using data from a total of 293 F2 intercross mice, we constructed weighted gene co-expression net ...[more]