Ontology highlight
ABSTRACT:
SUBMITTER: Kostic AD
PROVIDER: S-EPMC3266036 | biostudies-literature | 2012 Feb
REPOSITORIES: biostudies-literature
Genome research 20111018 2
The tumor microenvironment of colorectal carcinoma is a complex community of genomically altered cancer cells, nonneoplastic cells, and a diverse collection of microorganisms. Each of these components may contribute to carcinogenesis; however, the role of the microbiota is the least well understood. We have characterized the composition of the microbiota in colorectal carcinoma using whole genome sequences from nine tumor/normal pairs. Fusobacterium sequences were enriched in carcinomas, confirm ...[more]