Ontology highlight
ABSTRACT:
SUBMITTER: Marquez M
PROVIDER: S-EPMC3266400 | biostudies-literature | 2012 Feb
REPOSITORIES: biostudies-literature
Marquez Marcel M Huyvaert Marlène M Perry John R B JR Pearson Richard D RD Falchi Mario M Morris Andrew P AP Vivequin Sidonie S Lobbens Stéphane S Yengo Loïc L Gaget Stefan S Pattou Francois F Poulain-Godefroy Odile O Charpentier Guillaume G Carlsson Lena M S LM Jacobson Peter P Sjöström Lars L Lantieri Olivier O Heude Barbara B Walley Andrew A Balkau Beverley B Marre Michel M Froguel Philippe P Cauchi Stéphane S
Diabetes 20111230 2
It has recently been suggested that the low-frequency c.136-14_136-13insC variant in high-mobility group A1 (HMGA1) may strongly contribute to insulin resistance and type 2 diabetes risk. In our study, we attempted to confirm that HMGA1 is a novel type 2 diabetes locus in French Caucasians. The gene was sequenced in 368 type 2 diabetic case subjects with a family history of type 2 diabetes and 372 normoglycemic control subjects without a family history of type 2 diabetes. None of the 41 genetic ...[more]