Ontology highlight
ABSTRACT:
SUBMITTER: Zuckermann A
PROVIDER: S-EPMC3268050 | biostudies-literature | 2011
REPOSITORIES: biostudies-literature
Zuckermann Andreas A Wang Shoei-Shen SS Ross Heather H Frigerio Maria M Eisen Howard J HJ Bara Christoph C Hoefer Daniel D Cotrufo Maurizio M Dong Gaohong G Junge Guido G Keogh Anne M AM
Journal of transplantation 20110913
A six-month, multicenter, randomized, open-label study was undertaken to determine whether renal function is improved using reduced-exposure cyclosporine (CsA) versus standard-exposure CsA in 199 de novo heart transplant patients receiving everolimus and steroids ± induction therapy. Mean C(2) levels were at the low end of the target range in standard-exposure patients (n = 100) and exceeded target range in reduced-exposure patients (n = 99) throughout the study. Mean serum creatinine at Month 6 ...[more]