Rimonabant for neurocognition in schizophrenia: a 16-week double blind randomized placebo controlled trial.
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ABSTRACT:
SUBMITTER: Boggs DL
PROVIDER: S-EPMC3268840 | biostudies-literature | 2012 Feb
REPOSITORIES: biostudies-literature
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Rimonabant for neurocognition in schizophrenia: a 16-week double blind randomized placebo controlled trial.
Boggs Douglas L DL Kelly Deanna L DL McMahon Robert P RP Gold James M JM Gorelick David A DA Linthicum Jared J Conley Robert R RR Liu Fang F Waltz James J Huestis Marilyn A MA Buchanan Robert W RW
Schizophrenia research 20111203 2-3
<h4>Objective</h4>To examine the effect of rimonabant on neurocognitive impairments in people with schizophrenia.<h4>Methods</h4>Participants entered a 16-week double-blind, placebo-controlled, randomized clinical trial. A neurocognitive battery was administered at baseline and end of study.<h4>Results</h4>In comparison to rimonabant (20mg/day), placebo-treated participants exhibited a significant improvement on the Repeatable Battery for the Assessment of Neuropsychological Status total score. ...[more]
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