Ontology highlight
ABSTRACT:
SUBMITTER: Fine DM
PROVIDER: S-EPMC3269183 | biostudies-literature | 2012 Feb
REPOSITORIES: biostudies-literature
Fine Derek M DM Wasser Walter G WG Estrella Michelle M MM Atta Mohamed G MG Kuperman Michael M Shemer Revital R Rajasekaran Arun A Tzur Shay S Racusen Lorraine C LC Skorecki Karl K
Journal of the American Society of Nephrology : JASN 20111201 2
With earlier institution of antiretroviral therapy, kidney diseases other than HIV-associated nephropathy (HIVAN) predominate in HIV-infected persons. Outcomes for these diseases are typically worse among those infected with HIV, but the reasons for this are not clear. Here, we examined the role of APOL1 risk variants in predicting renal histopathology and progression to ESRD in 98 HIV-infected African Americans with non-HIVAN kidney disease on biopsy. We used survival analysis to determine time ...[more]