Animal models and molecular imaging tools to investigate lymph node metastases.
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ABSTRACT:
SUBMITTER: Servais EL
PROVIDER: S-EPMC3269816 | biostudies-literature | 2011 Aug
REPOSITORIES: biostudies-literature
Publications
Animal models and molecular imaging tools to investigate lymph node metastases.
Servais Elliot L EL Colovos Christos C Bograd Adam J AJ White Julie J Sadelain Michel M Adusumilli Prasad S PS
Journal of molecular medicine (Berlin, Germany) 20110510 8
Lymph node metastasis is a strong predictor of poor outcome in cancer patients. Animal studies of lymph node metastasis are constrained by difficulties in the establishment of appropriate animal models, limitations in the noninvasive monitoring of lymph node metastasis progression, and challenges in the pathologic confirmation of lymph node metastases. In this comprehensive review, we summarize available preclinical animal cancer models for noninvasive imaging and identification of lymph node me ...[more]
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