Triple-negative breast cancer: an update on neoadjuvant clinical trials.
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ABSTRACT:
SUBMITTER: Amos KD
PROVIDER: S-EPMC3270519 | biostudies-literature | 2012
REPOSITORIES: biostudies-literature
Publications
Triple-negative breast cancer: an update on neoadjuvant clinical trials.
Amos Keith D KD Adamo Barbara B Anders Carey K CK
International journal of breast cancer 20120124
Triple-negative breast cancer (TNBC) is an aggressive malignancy with a poor prognosis despite the high rates of response to chemotherapy. This scenario highlights the need to develop novel therapies and/or treatment strategies to reduce the mortality associated with TNBC. The neoadjuvant setting provides a model for rapid assessment of treatment efficacy with smaller patient accruals and over shorter periods of time compared to the traditional adjuvant setting. In addition, a clear surrogate en ...[more]
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