Ontology highlight
ABSTRACT:
SUBMITTER: Buttner CR
PROVIDER: S-EPMC3271932 | biostudies-literature | 2012 Jan
REPOSITORIES: biostudies-literature
Büttner Carina R CR Chechik Maria M Ortiz-Lombardía Miguel M Smits Callum C Ebong Ima-Obong IO Chechik Victor V Jeschke Gunnar G Dykeman Eric E Benini Stefano S Robinson Carol V CV Alonso Juan C JC Antson Alfred A AA
Proceedings of the National Academy of Sciences of the United States of America 20111229 3
Genome packaging into preformed viral procapsids is driven by powerful molecular motors. The small terminase protein is essential for the initial recognition of viral DNA and regulates the motor's ATPase and nuclease activities during DNA translocation. The crystal structure of a full-length small terminase protein from the Siphoviridae bacteriophage SF6, comprising the N-terminal DNA binding, the oligomerization core, and the C-terminal β-barrel domains, reveals a nine-subunit circular assembly ...[more]