Ontology highlight
ABSTRACT:
SUBMITTER: Bernstein J
PROVIDER: S-EPMC3272586 | biostudies-literature | 2012 Jan
REPOSITORIES: biostudies-literature
Bernstein Jade J Toth Eric A EA
World journal of biological chemistry 20120101 1
Nuclear RNA processing requires dynamic and intricately regulated machinery composed of multiple enzymes and their cofactors. In this review, we summarize recent experiments using Saccharomyces cerevisiae as a model system that have yielded important insights regarding the conversion of pre-RNAs to functional RNAs, and the elimination of aberrant RNAs and unneeded intermediates from the nuclear RNA pool. Much progress has been made recently in describing the 3D structure of many elements of the ...[more]