Ontology highlight
ABSTRACT:
SUBMITTER: Thomas S
PROVIDER: S-EPMC3273319 | biostudies-literature | 2011 Aug
REPOSITORIES: biostudies-literature
Thomas Stephanie S Waterman Peter P Chen Suelin S Marinelli Brett B Seaman Marc M Rodig Scott S Ross Robert W RW Josephson Lee L Weissleder Ralph R Kelly Kimberly A KA
Journal of nanomedicine & nanotechnology 20110801 112
Prostate cancer is the most commonly diagnosed non-skin malignancy in the United States and presents with a wide range of aggressiveness from extremely slow-growing to highly aggressive. There is a clinical need to determine the metastatic potential of the primary tumor to design the most appropriate treatment plan ranging from watchful waiting to more aggressive, invasive surgical treatments. In this study we have developed a nanoparticle based imaging agent that targets SPARC (Secreted Protein ...[more]