Ontology highlight
ABSTRACT:
SUBMITTER: Liu X
PROVIDER: S-EPMC3275333 | biostudies-literature | 2012 Mar
REPOSITORIES: biostudies-literature
Liu X X Yu L L Wang Q Q Pelletier J J Fausther M M Sévigny J J Malmström H S HS Dirksen R T RT Ren Y F YF
Journal of dental research 20111214 3
Dental pulpal nerve fibers express ionotropic adenosine triphosphate (ATP) receptors, suggesting that ATP signaling participates in the process of dental nociception. In this study, we investigated if the principal enzymes responsible for extracellular ATP hydrolysis, namely, nucleoside triphosphate diphosphohydrolases (NTPDases), are present in human dental pulp. Immunohistochemical and immunofluorescence experiments showed that NTPDase2 was predominantly expressed in pulpal nerve bundles, Rasc ...[more]