Transmission of two distinct HIV type 1 strains to an individual that were harbored for many years by another.
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ABSTRACT:
SUBMITTER: van Werkhoven MB
PROVIDER: S-EPMC3275923 | biostudies-literature | 2012 Feb
REPOSITORIES: biostudies-literature
Publications
Transmission of two distinct HIV type 1 strains to an individual that were harbored for many years by another.
van Werkhoven Maaike B MB Baan Elly E Bakker Margreet M Jurriaans Suzanne S Paxton William A WA Pollakis Georgios G
AIDS research and human retroviruses 20110726 2
The concept of transmission bottlenecks in HIV-1 infection is well established. Coinfections and superinfections have been increasingly documented and provide a founding cause for the expansion of viral diversity through recombination. It is still relatively unclear how HIV-1 will propagate and evolve in individuals infected with more than one viral strain. Here we report on the parallel transmission of genetically distant viral strains cocirculating in one individual over many years to a single ...[more]
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