Ontology highlight
ABSTRACT:
SUBMITTER: Imae R
PROVIDER: S-EPMC3276457 | biostudies-literature | 2012 Mar
REPOSITORIES: biostudies-literature
Imae Rieko R Inoue Takao T Nakasaki Yasuko Y Uchida Yasunori Y Ohba Yohsuke Y Kono Nozomu N Nakanishi Hiroki H Sasaki Takehiko T Mitani Shohei S Arai Hiroyuki H
Journal of lipid research 20111214 3
Mammalian phosphatidylinositol (PI) has a unique fatty acid composition in that 1-stearoyl-2-arachidonoyl species is predominant. This fatty acid composition is formed through fatty acid remodeling by sequential deacylation and reacylation. We recently identified three Caenorhabditis elegans acyltransferases (ACL-8, ACL-9, and ACL-10) that incorporate stearic acid into the sn-1 position of PI. Mammalian LYCAT, which is the closest homolog of ACL-8, ACL-9, and ACL-10, was originally identified as ...[more]