Ontology highlight
ABSTRACT:
SUBMITTER: Martin AL
PROVIDER: S-EPMC3276591 | biostudies-literature | 2009 Jun
REPOSITORIES: biostudies-literature
Martin Amanda L AL Hickey Jennifer L JL Ablack Amber L AL Lewis John D JD Luyt Leonard G LG Gillies Elizabeth R ER
Journal of nanoparticle research : an interdisciplinary forum for nanoscale science and technology 20090601 5
The imaging of molecular markers associated with disease offers the possibility for earlier detection and improved treatment monitoring. Receptors for gastrin-releasing peptide are overexpressed on prostate cancer cells offering a promising imaging target, and analogs of bombesin, an amphibian tetradecapeptide have been previously demonstrated to target these receptors. Therefore, the pan-bombesin analog [β-Ala11, Phe13, Nle14]bombesin-(7-14) was conjugated through a linker to dye-functionalized ...[more]