The genetic consequences of spatially varying selection in the panmictic American eel (Anguilla rostrata).

ABSTRACT: Our understanding of the genetic basis of local adaptation has recently benefited from the increased power to identify functional variants associated with environmental variables at the genome scale. However, it often remains challenging to determine whether locally adaptive alleles are actively maintained at intermediate frequencies by spatially varying selection. Here, we evaluate the extent to which this particular type of balancing selection explains the retention of adaptive genetic variation in the extreme situation of perfect panmixia, using the American eel (Anguilla rostrata) as a model. We first conducted a genome scan between two samples from opposite ends of a latitudinal environmental gradient using 454 sequencing of individually tagged cDNA libraries. Candidate SNPs were then

SUBMITTER: Gagnaire PA 

PROVIDER: S-EPMC3276646 | biostudies-literature | 2012 Feb

REPOSITORIES: biostudies-literature