Ontology highlight
ABSTRACT:
SUBMITTER: Nishimura Y
PROVIDER: S-EPMC3276738 | biostudies-literature | 2012 Mar
REPOSITORIES: biostudies-literature
Nishimura Yukihide Y Ii Masaaki M Qin Gangjian G Hamada Hiromichi H Asai Jun J Takenaka Hideya H Sekiguchi Haruki H Renault Marie-Ange MA Jujo Kentaro K Katoh Norito N Kishimoto Saburo S Ito Aiko A Kamide Christine C Kenny John J Millay Meredith M Misener Sol S Thorne Tina T Losordo Douglas W DW
The Journal of investigative dermatology 20111103 3 Pt 1
The antagonism of CXC-chemokine receptor 4 (CXCR4) with AMD3100 improves cardiac performance after myocardial infarction by augmenting the recruitment of endothelial progenitor cells (EPCs) from the bone marrow to the regenerating vasculature. We investigated whether AMD3100 may accelerate diabetes-impaired wound healing through a similar mechanism. Skin wounds were made on the backs of leptin receptor-deficient mice and treated with AMD3100 or saline. Fourteen days after treatment, wound closur ...[more]