Ontology highlight
ABSTRACT:
SUBMITTER: Lalor MK
PROVIDER: S-EPMC3276835 | biostudies-literature | 2009 Mar
REPOSITORIES: biostudies-literature
Lalor Maeve K MK Ben-Smith Anne A Gorak-Stolinska Patricia P Weir Rosemary E RE Floyd Sian S Blitz Rose R Mvula Hazzie H Newport Melanie J MJ Branson Keith K McGrath Nuala N Crampin Amelia C AC Fine Paul E M PE Dockrell Hazel M HM
The Journal of infectious diseases 20090301 6
Bacille Calmette-Guérin (BCG) vaccination induces a marked increase in the interferon (IFN)-gamma response to Mycobacterium tuberculosis purified protein derivative (Mtb PPD) in UK adolescents, but not in Malawian adolescents. We hypothesized that Mtb PPD-induced IFN-gamma after BCG vaccination would be similar in infants from these 2 countries. Infants were vaccinated with BCG during the first 3-13 weeks of life. Three months after BCG vaccination, 51 (100%) of 51 UK infants had an IFN-gamma re ...[more]