Ontology highlight
ABSTRACT:
SUBMITTER: Manca A
PROVIDER: S-EPMC3277554 | biostudies-literature | 2012 Feb
REPOSITORIES: biostudies-literature
Manca Annalisa A Capsoni Simona S Di Luzio Anna A Vignone Domenico D Malerba Francesca F Paoletti Francesca F Brandi Rossella R Arisi Ivan I Cattaneo Antonino A Levi-Montalcini Rita R
Proceedings of the National Academy of Sciences of the United States of America 20120125 6
Nerve growth factor (NGF) was discovered because of its neurotrophic actions on sympathetic and sensory neurons in the developing chicken embryo. NGF was subsequently found to influence and regulate the function of many neuronal and non neuronal cells in adult organisms. Little is known, however, about the possible actions of NGF during early embryonic stages. However, mRNAs encoding for NGF and its receptors TrkA and p75(NTR) are expressed at very early stages of avian embryo development, befor ...[more]