Ontology highlight
ABSTRACT:
SUBMITTER: Tan F
PROVIDER: S-EPMC3277750 | biostudies-literature | 2012 Feb
REPOSITORIES: biostudies-literature
Tan Fengwei F Jiang Ying Y Sun Nan N Chen Zhaoli Z Lv Yongzhuang Y Shao Kang K Li Ning N Qiu Bin B Gao Yibo Y Li Baozhong B Tan Xiaogang X Zhou Fang F Wang Zhen Z Ding Dapeng D Wang Jiwen J Sun Jian J Hang Jie J Shi Susheng S Feng Xiaoli X He Fuchu F He Jie J
Molecular & cellular proteomics : MCP 20111107 2
Lung cancer is the leading cause of cancer-related death in the world. To explore tumor biomarkers for clinical application, two-dimensional fluorescence difference gel electrophoresis and subsequent MALDI-TOF/TOF mass spectrometry were performed to identify proteins differentially expressed in 12 pairs of lung squamous cell tumors and their corresponding normal tissues. A total of 28 nonredundant proteins were identified with significant alteration in lung tumors. The up-regulation of isocitrat ...[more]