Ontology highlight
ABSTRACT:
SUBMITTER: Rogers RS
PROVIDER: S-EPMC3277762 | biostudies-literature | 2012 Feb
REPOSITORIES: biostudies-literature
Molecular & cellular proteomics : MCP 20111129 2
We investigate the role of glial cell activation in the human optic nerve caused by raised intraocular pressure, and their potential role in the development of glaucomatous optic neuropathy. To do this we present a proteomics study of the response of cultured, optic nerve head astrocytes to biomechanical strain, the magnitude and mode of strain based on previously published quantitative models. In this case, astrocytes were subjected to 3 and 12% stretches for either 2 h or 24 h. Proteomic metho ...[more]