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PIE the search: searching PubMed literature for protein interaction information.


ABSTRACT:

Motivation

Finding protein-protein interaction (PPI) information from literature is challenging but an important issue. However, keyword search in PubMed(®) is often time consuming because it requires a series of actions that refine keywords and browse search results until it reaches a goal. Due to the rapid growth of biomedical literature, it has become more difficult for biologists and curators to locate PPI information quickly. Therefore, a tool for prioritizing PPI informative articles can be a useful assistant for finding this PPI-relevant information.

Results

PIE (Protein Interaction information Extraction) the search is a web service implementing a competition-winning approach utilizing word and syntactic analyses by machine learning techniques. For easy user access, PIE the search provides a PubMed-like search environment, but the output is the list of articles prioritized by PPI confidence scores. By obtaining PPI-related articles at high rank, researchers can more easily find the up-to-date PPI information, which cannot be found in manually curated PPI databases.

Availability

http://www.ncbi.nlm.nih.gov/IRET/PIE/.

SUBMITTER: Kim S 

PROVIDER: S-EPMC3278758 | biostudies-literature | 2012 Feb

REPOSITORIES: biostudies-literature

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Publications

PIE the search: searching PubMed literature for protein interaction information.

Kim Sun S   Kwon Dongseop D   Shin Soo-Yong SY   Wilbur W John WJ  

Bioinformatics (Oxford, England) 20111222 4


<h4>Motivation</h4>Finding protein-protein interaction (PPI) information from literature is challenging but an important issue. However, keyword search in PubMed(®) is often time consuming because it requires a series of actions that refine keywords and browse search results until it reaches a goal. Due to the rapid growth of biomedical literature, it has become more difficult for biologists and curators to locate PPI information quickly. Therefore, a tool for prioritizing PPI informative articl  ...[more]

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