Ontology highlight
ABSTRACT:
SUBMITTER: Huang X
PROVIDER: S-EPMC3280205 | biostudies-literature | 2012
REPOSITORIES: biostudies-literature
Huang Xin X Hepkema Bouke B Nolte Ilja I Kushekhar Kushi K Jongsma Theo T Veenstra Rianne R Poppema Sibrand S Gao Zifen Z Visser Lydia L Diepstra Arjan A van den Berg Anke A
PloS one 20120215 2
HLA-A2 protects from EBV+ classical Hodgkin lymphoma (cHL) in Western Europe, but it is unknown whether this protective effect also exists in the Chinese population. We investigated the association of HLA-A2 and specific common and well documented HLA-A2 subtypes with EBV stratified cHL patients (n = 161) from the northern part of China. Quantitative-PCR and sequence-based subtyping was performed to identify HLA-A2 positive samples and their subtypes. 67 (42%) of the cHL patients were EBV+. Ther ...[more]