Fast patient-specific Monte Carlo brachytherapy dose calculations via the correlated sampling variance reduction technique.

ABSTRACT:

Purpose

To demonstrate potential of correlated sampling Monte Carlo (CMC) simulation to improve the calculation efficiency for permanent seed brachytherapy (PSB) implants without loss of accuracy.

Methods

CMC was implemented within an in-house MC code family (PTRAN) and used to compute 3D dose distributions for two patient cases: a clinical PSB postimplant prostate CT imaging study and a simulated post lumpectomy breast PSB implant planned on a screening dedicated breast cone-beam CT patient exam. CMC tallies the dose difference, ΔD, between highly correlated histories in homogeneous and heterogeneous geometries. The heterogeneous geometry histories were derived from photon collisions sampled in a geometrically identical but purely homogeneous medium geometry, by altering th

SUBMITTER: Sampson A 

PROVIDER: S-EPMC3281974 | biostudies-literature | 2012 Feb

REPOSITORIES: biostudies-literature