Ontology highlight
ABSTRACT:
SUBMITTER: Prole DL
PROVIDER: S-EPMC3283738 | biostudies-literature | 2012
REPOSITORIES: biostudies-literature
Prole David L DL Marrion Neil V NV
PloS one 20120221 2
K(+) channels play a vital homeostatic role in cells and abnormal activity of these channels can dramatically alter cell function and survival, suggesting that they might be attractive drug targets in pathogenic organisms. Pathogenic protozoa lead to diseases such as malaria, leishmaniasis, trypanosomiasis and dysentery that are responsible for millions of deaths each year worldwide. The genomes of many protozoan parasites have recently been sequenced, allowing rational design of targeted therap ...[more]