Evolution of a large, conserved, and syntenic gene family in insects.
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ABSTRACT:
SUBMITTER: Shah N
PROVIDER: S-EPMC3284338 | biostudies-literature | 2012 Feb
REPOSITORIES: biostudies-literature
Publications
Evolution of a large, conserved, and syntenic gene family in insects.
Shah Neethu N Dorer Douglas R DR Moriyama Etsuko N EN Christensen Alan C AC
G3 (Bethesda, Md.) 20120201 2
The Osiris gene family, first described in Drosophila melanogaster, is clustered in the genomes of all Drosophila species sequenced to date. In D. melanogaster, it explains the enigmatic phenomenon of the triplo-lethal and haploinsufficient locus Tpl. The synteny of Osiris genes in flies is well conserved, and it is one of the largest syntenic blocks in the Drosophila group. By examining the genome sequences of other insects in a wide range of taxonomic orders, we show here that the gene family ...[more]
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